Stage 4 Breast Cancer is one of the most challenging problems in Oncology practice. Treatment options for Metastatic Breast Cancer with Hormone Receptor Positive Nature and Her2 Neu Negative Receptors are diverse and so far, there is no superior treatment option over the others. The main concern of patients with stage 4 Breast Cancer is to control disease spread, improve the quality of life, and if possible, to improve the survival rate.
The standard medical oncology practice now is to administer a Tyrosine Kinase Inhibitor palbociclib (Ibrance) and an Aromatase Inhibitor (Anti Estrogen) Letrozole or Exemestane. This regimen combines the anti cancer effects of the Ibrance and the hormone suppressive effects of the Exemestane , however, with the combination of the two agents, we expect to have more toxicities and side effects especially from the hormone suppression such as fatigue, tiredness hot flushes and sweating, so, many medical oncologists are searching for a less toxic possibly more effective means for treatment of patients with Stage 4 Breast Cancer.
For that reason, a group of medical oncology researchers in South Korea compared 2 treatment options the first was the one mentioned above i.e. a combination of Ibrance and Exemestane (92 patients) and the second one was a single agent oral Chemotherapy (Capecitabine) (92 patients) between June 15th 2016 and December 10th 2018.
Although the aim of this study was to find an alternative to the standard combination treatment of Ibrance and Exemestane to avoid the toxicities and the side effects of this treatment, the final results showed that this standard treatment was more effective than the new experimental treatment (Capecitabine) in terms of improved disease free survival
To get more information about the scientific details of this research you can check this link https://pubmed.ncbi.nlm.nih.gov/31668850/
Role of Naturopathic Medicine
In view of the development of side effects with the standard Oncology Practice of Ibrance and Exemestane or other hormone suppressive agents, it makes lot of sense to find ways to curb or control the side effects of these interventions. This will not only improve the quality of life of these patients and supporting their overall health, but it also, encourage them to continue this treatment with the least of the side effects of these interventions.
Naturopathic Interventions can improve the side effects of the hormonal blockage by working on the lifestyle, nutrition, and using some herbs that would not interfere with the effects of the Ibrance and Exemestane and at the same time to achieve the goal of reducing the side effects of these interventions. Other measures also include Acupuncture with the aim of releasing the heat for women who develop hot flushes, flashes and excess sweating.
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Grimsby and Hamilton https://www.ontarionaturopathicclinic.ca/site/contact-grimsby